主持课题项目：
1.国家自然科学基金委面上项目
2.亚搏手机版网页登陆自主科研项目
代表性论文:(*corresponding author,#co-first author)
1.Qiangqiang Sun, Kang Xiong, Yuncong Yuan, Jing Yu, Lianjuan Yang, Chao Shen, Chang Su*, and Yang Lu*. (2019) Inhibiting fungal echinocandin resistance by small-molecular disruption of geranylgeranyltransferase type I activity. Antimicrobial Agents and Chemotherapy: 02406-19
2.Yang Lu*#; Chang Su#; Shatarupa Ray; Yuncong Yuan; Haoping Liu*. (2019) CO2 signaling through the Ptc2-Ssn3 axis governs sustained hyphal development of Candida albicans by reducing Ume6 phosphorylation and degradation. mBio 10(1)
3.Chang Su#; Jing Yu#; Qiangqiang Sun; Qian Liu; Yang Lu*. (2018) Hyphal induction under the condition without inoculation in Candida albicans is triggered by Brg1-mediated removal of NRG1 inhibition. Molecular Microbiology 108(4): 410-423
4.Chang Su; Jing Yu; Yang Lu*. (2018) Hyphal development in Candida albicans from different cell states. Current Genetics 64(6): 1239-1243
5.Chang Su#; Yang Lu#; Haoping Liu. (2016) N-acetylglucosamine sensing by a GCN5-related N-acetyltransferase induces transcription via chromatin histone acetylation in fungi. Nature Communications 7:12916
6.Yang Lu, Chang Su, and Haoping Liu. (2014) Candida albicans hyphal initiation and elongation. Trends in Microbiology 22(12): 707-14.
7.Yang Lu#, Chang Su#, Ohimai Unoje, and Haoping Liu*. (2014) Quorum sensing controls hyphal initiation in Candida albicans through Ubr1-mediated protein degradation. Proc Natl Acad Sci 111(5): 1975-80.
8.Yang Lu, Chang Su, Norma V. Solis, Scott G. Filler, and Haoping Liu*. (2013) Synergistic regulation of hyphal elongation by hypoxia, CO2, and nutrient conditions controls the virulence of Candida albicans. Cell Host & Microbe 14(5): 499-509.
9.Chang Su#, Yang Lu#, and Haoping Liu*. (2013) Reduced TOR signaling sustains hyphal development in Candida albicans by lowering Hog1 basal activity. Molecular Biology of the Cell 24(3): 385-97. (* equal contribution)
10.Yang Lu, Chang Su, and Haoping Liu*. (2012) A GATA transcription factor recruits Hda1 in response to reduced Tor1 signaling to establish a hyphal chromatin state in Candida albicans. PLoS Pathogens 8(4): e1002663.
11.Yang Lu, Chang Su, Allen Wang, and Haoping Liu*. (2011) Hyphal development in Candida albicans requires two temporally linked changes in promoter chromatin for initiation and maintenance. PLoS Biology 9(7): e1001105.
12.Yang Lu, Chang Su, Xuming Mao, Prashna Pala Raniga, Haoping Liu*, and Jiangye Chen*. (2008) Efg1-mediated recruitment of NuA4 to promoters is required for hypha-specific Swi/Snf binding and activation in Candida albicans. Molecular Biology of the Cell 19(10): 4260-72.
招生招聘：
热忱欢迎本科生、硕士生、博士生、博士后加入本实验室。
每年拟接收1-2名本科生，2名硕士生和1名博士生，博士后可以随时联系。
